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Research on pharmaceutical intermediates

Research on the Current Development Status of the Industry

- Market size: Its market size is closely related to the development of the pharmaceutical industry. According to statistics, the global market size of pharmaceutical intermediates has reached hundreds of billions of US dollars in 2024. It is predicted that it will exceed 100 billion US dollars in 2025, with a compound annual growth rate of over 10%. The Chinese market is also growing rapidly, reaching a scale of 33.5 billion US dollars in 2024 and expected to reach 36 billion US dollars in 2025, representing a year-on-year growth of 11.5%.
- Competitive landscape: The global competition is fierce. Sinopharm Group, Huayao Group, BASF of Germany, DuPont of the United States, etc. have significant competitive advantages. In China, the East China region, leveraging its advantages in scientific research and industrial chains, accounts for approximately 45% of the domestic market share.
- Policy environment: The increasingly strict environmental regulations in various countries have prompted enterprises to develop green and environmentally friendly products. Meanwhile, some countries will introduce supportive policies. For instance, China encourages the development of high-end pharmaceutical intermediate products to facilitate industrial upgrading.

Technical research

- Production process: The mainstream is chemical synthesis, but it generates a lot of by-products and causes significant pollution. With the development of green chemistry, technologies such as biocatalysis and chiral resolution have received attention. Biocatalysis uses enzymes or microorganisms as catalysts, with mild reactions and environmental friendliness. Chiral resolution can obtain high-purity single enantiomers, meeting the demands of high-end drugs.
- Technological innovation: Focusing on the optimization of synthetic routes, the development of new catalysts, and the improvement of separation and purification technologies, it can reduce reaction steps, increase yield and product purity.

Research on Industrial chains

The upstream mainly involves the supply of basic chemical raw materials. Fluctuations in their prices can easily affect the production costs of intermediates. In recent years, the increase in chemical raw material prices has intensified the cost control pressure on many enterprises.
Downstream: The demand for manufacturing related pharmaceutical products, as well as the research and production of popular drugs such as innovative drugs, anti-tumor drugs, and cardiovascular disease treatment drugs, is driving the continuous rise in the demand for corresponding high-end intermediates.

Research on Development Trends

This includes basic research such as exploring new reaction and synthetic routes and uncovering the application potential of new materials, as well as the practice of emerging technologies like green chemistry, intelligent manufacturing, and biosynthesis, to meet environmental protection requirements and enhance production efficiency. Meanwhile, the demand for personalized and customized intermediate products has gradually become an important trend in the development of niche fields.


Post time: Aug-13-2025