HGH

Human growth hormone (HGH) is a peptide hormone secreted by the pituitary gland. Its main physiological functions include promoting growth and development, regulating metabolism, maintaining tissue repair and immune function. It has a significant impact on the development of bones, muscles, internal organs and energy balance, and its effect lasts throughout the entire life cycle.

1. Promote growth and development

Bone growth: HGH binds to receptors in tissues such as the liver, stimulating the secretion of insulin-like growth factor (IGF-1), directly promoting the proliferation and differentiation of epiphyseal chondrocytes and driving longitudinal bone growth. Insufficient secretion during childhood and adolescence can lead to dwarfism, while excessive secretion can cause gigantism. 1.

Muscle development: HGH enhances protein synthesis, reduces muscle breakdown, and maintains muscle mass and strength. This is also one of the reasons why athletes illegally use HGH to enhance their athletic performance. 2.

Second, regulate metabolic balance

Protein metabolism: HGH promotes protein synthesis by activating amino acid transporters, increasing the uptake of amino acids by muscles. 1.

Fat metabolism: Stimulate the activity of fat-decomposing enzymes, accelerate fat breakdown for energy supply, and long-term insufficient secretion may lead to central obesity. 2.

Glucose metabolism: Antagonizes the effect of insulin, inhibits the uptake of glucose by peripheral tissues, and raises blood sugar levels. Long-term excessive intake may increase the risk of diabetes. 3.

Iii. Maintain tissue repair and regeneration

Cell proliferation: HGH promotes the regeneration of skin, vascular endothelial cells, etc., and accelerates wound healing. 1.

Organ function: Maintaining the structural integrity of internal organs such as the heart and kidneys. A decrease in secretion after adulthood may be related to the decline of organ function. 2.

Bone health: Synergistically regulate bone metabolism with calcium and vitamin D to prevent osteoporosis. 3.

Fourth, it affects immune function

HGH can enhance the activity of immune cells (such as T cells and NK cells), promote antibody production, and improve the body’s ability to resist infection. However, excessive secretion may cause immune disorders.